Prof. Dr. André Scheffel

Group Leader

Department for Aquatic Microbiology

Felix-Hausdorff-Straße 8 - 1. floor - room: 1.54

17489 Greifswald

phone: +49 (0)3834 420 5902
fax:      +49 (0)3834 420 5909
email:   scheffela[at]

Curriculum Vitae
since 10/2023 Professor for Aquatic Microbiology, University of Greifswald
2021 – 2023 Professorship for Molecular Cell Biology of Microalgae (Heisenberg), Technical University of Dresden
2010 – 2021 Emmy Noether group leader at the Max-Planck Institute of Molecular Plant Physiology, Potsdam
2007 – 2010 DFG-funded postdoctoral fellow at the Georgia Institute of Technology, Atlanta, USA
2003 – 2007 PhD Student, Max-Planck Institute for Marine Microbiology, Bremen
1997 – 2003 Study of Biotechnology, Technische Universität Berlin
  • Skeffington A., Fischer A., Sviben S., Brzezinka M., Górka M., Bertinetti L., Woehle C.,  Huettel B., Graf A. and Scheffel A. A joint proteomic and genomic investigation provides insights into the mechanism of calcification in coccolithophores. Nat Commun 14, 3749 (2023) [Publisher]
  • Silvestri A., Pätzold J., Fratzl P., Scheffel A.* and Faivre D.* SERS micro-spectroscopy enables the direct characterization of biomineral-associated organic material on single calcareous microskeletons. J. Phy. Chem. Lett. 11: 8623 -8629 (2020) [Pubmed]
  • Skeffington A.W. and Donath A. ProminTools: Shedding light on proteins of unknown function in biomineralization with user friendly tools illustrated using mollusc shell matrix protein sequences.PeerJ 8:9852. (2020) [Pubmed]
  • Hartmann S., Preick M., Abelt S., Scheffel A. and Hofreiter M. Annotated genome sequences of the carnivorous plant Roridula gorgonias and a non-carnivorous relative, Clethra arborea.BMC Res. Notes 13: 426 (2020) [Pubmed]
  • Skeffington A.W., Grimm A., Schönefeld S., Petersen K. and Scheffel A. An efficient method for the plating of haploid and diploid Emiliania huxleyi on solid medium which does not result in ploidy changes.J. Phycol. 56(1): 238-242 (2019) [Pubmed]
  • Gal A., Sorrentino A., Kahil K., Pereiro E., Faivre D. and Scheffel A. Native-state imaging of calcifying and non-calcifying microalgae reveals similarities in their calcium storage organelles.Proc. Natl. Acad. Sci. U.S.A. 115(43): 11000-11005 (2018) [Pubmed]
  • Gal A., Sviben S., Wirth R., Schreiber A., Lassalle-Kaiser B., Faivre D. and Scheffel A. Trace-element incorporation into intracellular pools uncovers calcium-pathways in a coccolithophore. Adv. Sci. 4: 1700088 (2017) [Pubmed]
  • Gal A., Wirth R., Barkay Z., Eliaz N., Scheffel A. and Faivre D. Templated and self-limiting calcite formation directed by coccolith organic macromolecules.Chem. Commun. 53: 7740-7743 (2017) [Pubmed]
  • Skeffington A.W. and Scheffel A. Exploiting algal mineralization for nanotechnology: Bringing coccoliths to the fore.Curr. Opin. Biotechnol. 49: 57-63 (2017) [Pubmed]
  • Ishihara H., Moraes T.A., Pyl E-T., Schulze W., Obata T., Scheffel A., Fernie A.R., Sulpice R. and Stitt M. Growth rate correlates negatively with protein turnover in Arabidopsis accessions.Plant J. 93: 416-429 (2017) [Pubmed]
  • Becker S., Scheffel A., Polz M. and Hehemann J.H. Accurate quantification of laminarin in marine organic matter with enzymes from marine microbes.Appl. Environ. Microbiol. 93: e03389-16 (2017) [Pubmed]
  • Bareither N., Scheffel A. and Metz J. Distribution of polyploid plants in the common annual Brachypodium distachyon (s.l.) in Israel is not linearly correlated with aridity.IJPS 64: 83-92 (2017)
  • Gal A., Wirth R., Kopka J., Fratzl P., Faivre D. and Scheffel A. Macromolecular recognition directs calcium ions to coccolith mineralization sites.Science 353: 590-593 (2016) [Pubmed]
  • Hood M.A., Leemreize H., Scheffel A. and Faivre D. Lattice distortions in coccolith calcite crystals originate from occlusion of biomacromolecules.J. Struct. Biol. 196: 147-154 (2016) [Pubmed]
  • Sviben S., Gal A., Hood M.A., Bertinetti L., Politi Y., Bennet M., Krishnamoorthy P., Schertel A., Wirth R., Sorrentino A., Pereiro E., Faivre D. and Scheffel A.A vacuole-like compartment concentrates a disordered calcium phase in a key coccolithophorid alga.Nat. Commun. 7: 11228 (2016) [Pubmed]
  • Addadi L., Gal A., Faivre D., Scheffel A. and Weiner S. Control of biogenic nanocrystal formation in biomineralization.Israel Journal of Chemistry 56:227-241 (2016) [Publisher]
  • Kotzsch A., Pawolski D., Milentyev A., Shevchenko A., Scheffel A., Poulsen N., Shevchenko A. and Kröger N. Biochemical composition and assembly of biosilica-associated insoluble organic matrices from the diatom Thalassiosira pseudonana J. Biol. Chem. 291:4982-4997 (2016) [Pubmed]
  • Obata T., Schoenefeld S., Krahnert I., Bergmann S., Scheffel A. and Fernie A. Gas-Chromatography Mass-Spectrometry (GC-MS) based metabolite profiling reveals mannitol as a major storage carbohydrate in the coccolithophorid alga Emiliania huxleyi.Metabolites 3: 168-184 (2013) [Pubmed]
  • Poulsen N., Scheffel A., Sheppard V.C., Chesley, P.M. and Kröger N. Pentalysine clusters mediate silica targeting of silaffins in Thalassiosira pseudonana.J. Biol. Chem. 288: 20100 20109 (2013) [Pubmed]
  • Sheppard V.C., Scheffel A., Poulsen N. and Kröger, N.Live diatom silica immobilization of multimeric and redox-active enzyme. Appl. Environ. Microbiol. 78: 211 218 (2012) [Pubmed]
  • Scheffel A., Poulsen N., Shian S. and Kröger N. Nanopatterned protein microrings from a diatom that direct silica morphogenesis.Proc. Natl. Acad. Sci. U.S.A. 108: 3175 3180 (2011) [Pubmed]
  • Katzmann E., Scheffel A., Gruska M., Plitzko J. and Schüler D. Loss of the actin-like protein MamK has pleiotropic effects on magnetosome formation and chain assembly in Magnetospirillum gryphiswaldense.Mol. Microbiol. 77: 208-224 (2010) [Pubmed]
  • Scheffel A., Gärdes A., Grünberg, K., Wanner G. and Schüler D.The major magnetosome proteins MamGFDC are not essential for magnetite biomineralization in Magnetospirillum gryphiswaldense but regulate the size of magnetosome crystals.J. Bacteriol. 190: 377-386 (2008) [Pubmed]
  • Scheffel A. and Schüler D. The acidic repetitive domain of the Magnetospirillum gryphiswaldense MamJ protein displays hypervariability but is not required for magnetosome chain assembly. J. Bacteriol. 189: 6437-6446 (2007) [Pubmed]
  • Scheffel A., Gruska M., Faivre D., Linaroudis A., Graumann, P.L., Plitzko J.M. and Schüler D. An acidic protein aligns magnetosomes along a filamentous structure in magnetotactic bacteria. Nature 440: 110-114 (2006) [Pubmed]
  • Dalisay D.S., Webb J.S., Scheffel A., Svenson C., James S., Holmstrom C., Egan S. and Kjelleberg S. A mannose-sensitive haemagglutinin (MSHA)-like pilus promotes attachment of Pseudoalteromonas tunicata cells to the surface of the green alga Ulva australis.Microbiology-SGM 152: 2875-2883 (2006) [Pubmed]
  • Scheffel, A. and Schüler D. Magnetosomes of magnetotactic bacteria. In J. M. Shively (ed.), Prokaryotic inclusions, compartments and assemblages, vol. 1. Springer, Heidelberg (2006)
  • Schübbe S., Kube M., Scheffel A., Wawer C., Heyen U., Meyerdierks A., Madkour M.H., Mayer F., Reinhardt R. and Schüler, D. Characterization of a spontaneous nonmagnetic mutant of Magnetospirillum gryphiswaldense reveals a large deletion comprising a putative magnetosome island.J. Bacteriol. 185: 5779-5790 (2003) [Pubmed]