Alexander Graf

MSc Molecular Biology & Physiology

Department for Microbial Physiology and Molecular Biology

Felix-Hausdorff-Straße 8 - 1. floor - room-nr.: 1.07

17489 Greifswald

phone: +49 (0)3834 420 5951
fax:      +49 (0)3834 420 5902
email:   alexander.graf(at)uni-greifswald(dot)de



Curriculum Vitae
08/2019 – 08/2020 Parental leave
12/2018 – 08/2019 Regulatory Affairs Manager, Cheplapharm Arzneimittel GmbH, Greifswald, Germany
10/2016 – 02/2017 Parental leave
10/2014 – 11/2018 PhD student, University of Greifswald, Germany,
Thesis: In vitro and in vivo analyses of mono- and mixed-species biofilms formed by microbial pathogens (DFG TRR 34)
10/2012 - 09/2014 Studies of Molecular Biology & Physiology M.Sc., University of Greifswald, Germany, Thesis: Evolution and interactions of co-colonizing Staphylococcus aureus and Pseudomonas aeruginosa cystic fibrosis isolates
10/2009 - 09/2012 Studies of Biochemistry B.Sc., University of Greifswald, Germany, Thesis: Proteomic analysis of interactions in mixed species biofilms formed by uropathogenic Pseudomonas aeruginosa and Proteus mirabilis strains
Research Interests
  • Physiology and ECM architecture of Staphylococcus aureus biofilms
  • Antimicrobial effects of non-thermal plasma on Candida albicans biofilms
  • Multi-omics analyses of cystic fibrosis sputum focusing on microbial pathogens
  • Interactions between Staphylococcus aureus and Pseudomonas aeruginosa in mixed-species biofilms
Awards and achievements
  • 05/2017: Invited speaker, Talk “Panoramic View on Staphylococcus aureus biofilm physiology”, invited by Dr. Jennifer Geddes-McAlister and Dr. Cezar Khursigara, Department of Molecular and Cellular Biology, University of Guelph, Canada
Publication list
  • A. C. Graf, A. Leonard, M. Schäuble, L. M. Rieckmann, J. Hoyer, S. Maaß, M. Lalk, D. Becher, J. Panè-Farrè, K. Riedel, Virulence factors produced by Staphylococcus aureus biofilms have a moonlighting function contributing to biofilm integrity, Molecular and Cellular Proteomics, 2019, PMID: 30850421
  • O. Handorf, T. Weihe, S. Bekeschus, A. C. Graf, U. Schnabel, K. Riedel, J. Ehlbeck, Non-thermal plasma jet treatment negatively affects viability and structure of C. albicans SC5314 biofilms,Applied and Environmental Microbiology, 2018, PMID: 30143511
  • O. Handorf, U. Schnabel, Andrè Bösel, T. Weihe, S. Bekeschus, A. C. Graf, K. Riedel, J. Ehlbeck, Antimicrobial effects of microwave-induced plasma torch (MiniMIP) treatment on Candida albicans biofilms, Microbial Biotechnology, 2019, PMID: 31264377
  • A. C. Graf, J. Striesow, T. Sura, D. H. Pieper, M. Lalk, D. Becher, B. Kahl, K. Riedel, Combined metaproteome and metabolome analysis of cystic fibrosis sputum focusing on microbial pathogens, PLOS One, in preparation