Dr. Jan Pané-Farré

Senior Scientist, Subgroup Leader

Department for Microbial Physiology and Molecular Biology

Felix-Hausdorff-Straße 8 - 1. floor - room: 1.51

17489 Greifswald

phone: +49 (0)3834 420 5915
fax:      +49 (0)3834 420 5902
email:   janpf[at]uni-greifswald.de

Curriculum Vitae
1/2016-5/2016Research visit at UCLA, USA in the lab of Beth Lazazzera Department of Microbiology, Immunology & Molecular Genetic
since 2014Research Group leader at the Institute for Microbiology, University Greifswald, in the group of Katharina Riedel
2008-2014Post-Doc at the Institute for Microbiology, University Greifswald, in the group Michael Hecker
03/2013-08/2013Parental leave
02/2011-04/2011Parental leave
11/2002-4/2008 PhD thesis at the Institute for Microbiology with Michael Hecker, University Greifswald
2007Participant 57th Meeting of Nobel Laureates in Lindau, Germany
2001 - 2002Fellowship Studienstiftung des deutschen Volkes
1997-2002Study of Human biology, Ernst-Moritz-Arndt-University Greifswald, Germany (Prof. Dr. Michael Hecker)
Publications
  • Reiss S, Pané-Farré J, Fuchs S, François P, Liebeke M, Schrenzel J, Lindequist U, Lalk M, Wolz C, Hecker M, Engelmann S. Global analysis of the Staphylococcus aureus response to mupirocin. Antimicrob Agents Chemother.2012 Feb;56(2):787-804. PMID: 22106209.

  • Pagels M, Fuchs S, Pané-Farré J, Kohler C, Menschner L, Hecker M, McNamarra PJ, Bauer MC, von Wachenfeldt C, Liebeke M, Lalk M, Sander G, von Eiff C, Proctor RA, Engelmann S. Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus. Mol Microbiol.2010 Jun 1;76(5):1142-61. PMID: 20374494.

  • Hempel K, Pané-Farré J, Otto A, Sievers S, Hecker M, Becher D. Quantitative cell surface proteome profiling for SigB-dependent protein expression in the human pathogen Staphylococcus aureus via biotinylation approach. J Proteome Res.2010 Mar 5;9(3):1579-90. PMID: 20108986.

  • Becher D, Hempel K, Sievers S, Zühlke D, Pané-Farré J, Otto A, Fuchs S, Albrecht D, Bernhardt J, Engelmann S, Völker U, van Dijl JM, Hecker M. A proteomic view of an important human pathogen–towards the quantification of the entire Staphylococcus aureus proteome. PLoS One.2009 Dec 4;4(12):e8176. PMID: 19997597.

  • Pané-Farré J, Jonas B, Hardwick SW, Gronau K, Lewis RJ, Hecker M, Engelmann S. Role of RsbU in controlling SigB activity in Staphylococcus aureus following alkaline stress. J Bacteriol.2009 Apr;191(8):2561-73. PMID: 19201800.

  • Hecker M, Pané-Farré J, Völker U. SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. Annu Rev Microbiol.2007;61:215-36. PMID: 18035607.

  • Hardwick SW, Pané-Farré J, Delumeau O, Marles-Wright J, Murray JW, Hecker M, Lewis RJ. Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis. J Biol Chem.2007 Apr 13;282(15):11562-72. PMID: 17303566.

  • Pané-Farré J, Jonas B, Förstner K, Engelmann S, Hecker M. The sigmaB regulon in Staphylococcus aureus and its regulation. Int J Med Microbiol.2006 Aug;296(4-5):237-58. PMID: 16644280.

  • Pané-Farré J, Lewis RJ, Stülke J. The RsbRST stress module in bacteria: a signalling system that may interact with different output modules. J Mol Microbiol Biotechnol.2005;9(2):65-76. PMID: 16319496.

  • Lama A, Pané-Farré J, Chon T, Wiersma AM, Sit CS, Vederas JC, Hecker M, Nakano MM. Response of methicillin-resistant Staphylococcus aureus to amicoumacin A. PLoS One.2012;7(3):e34037. PMID: 22479511.

  • Pförtner H, Burian MS, Michalik S, Depke M, Hildebrandt P, Dhople VM, Pané-Farré J, Hecker M, Schmidt F, Völker U. Activation of the alternative sigma factor SigB of Staphylococcus aureus following internalization by epithelial cells – an in vivo proteomics perspective. Int J Med Microbiol.2014 Mar;304(2):177-87. PMID: 24480029.

  • Fuchs S, Zühlke D, Pané-Farré J, Kusch H, Wolf C, Reiß S, Binh le TN, Albrecht D, Riedel K, Hecker M, Engelmann S. Aureolib – a proteome signature library: towards an understanding of staphylococcus aureus pathophysiology. PLoS One.2013 Aug 13;8(8):e70669. PMID: 23967085.

  • Dangel A, Ackermann N, Abdel-Hadi O, Maier R, Önder K, Francois P, Müller CW, Pané-Farré J, Engelmann S, Schrenzel J, Heesemann J, Lindermayr C. A de novo-designed antimicrobial peptide with activity against multiresistant Staphylococcus aureus acting on RsbW kinase. FASEB J.2013 Nov;27(11):4476-88. PMID: 23901070.

  • Lâm TT, Giese B, Chikkaballi D, Kühn A, Wolber W, Pané-Farré J, Schäfer D, Engelmann S, Fraunholz M, Sinha B. Phagolysosomal integrity is generally maintained after Staphylococcus aureus invasion of nonprofessional phagocytes but is modulated by strain 6850. Infect Immun.2010 Aug;78(8):3392-403. PMID: 20530231.

  • Liebeke M, Dörries K, Zühlke D, Bernhardt J, Fuchs S, Pané-Farré J, Engelmann S, Völker U, Bode R, Dandekar T, Lindequist U, Hecker M, Lalk M. A metabolomics and proteomics study of the adaptation of Staphylococcus aureus to glucose starvation. Mol Biosyst.2011 Apr;7(4):1241-53. PMID: 21327190.

  • Hain T, Hossain H, Chatterjee SS, Machata S, Volk U, Wagner S, Brors B, Haas S, Kuenne CT, Billion A, Otten S, Pane-Farre J, Engelmann S, Chakraborty T. Temporal transcriptomic analysis of the Listeria monocytogenes EGD-e sigmaB regulon. BMC Microbiol.2008 Jan 28;8:20. PMID: 18226246.

  • Fuchs S, Pané-Farré J, Kohler C, Hecker M, Engelmann S. Anaerobic gene expression in Staphylococcus aureus. J Bacteriol.2007 Jun;189(11):4275-89. PMID: 17384184.

  • Rogasch K, Rühmling V, Pané-Farré J, Höper D, Weinberg C, Fuchs S, Schmudde M, Bröker BM, Wolz C, Hecker M, Engelmann S. Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains. J Bacteriol.2006 Nov;188(22):7742-58. PMID: 17079681.